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proposal for friendly spatialdata_io.stereoseq function

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#355 1 comment 0 reactions 0 assignees View on GitHub

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Assessment

Difficulty
5/5
Estimated time
Over a week
Newbie friendliness
25/100
Issue type
Feature
Clarity
Needs clarification
Activity status
Stale
Tech stack
python

Research direction

Start by inspecting the spatialdata_io.stereoseq reader and comparing the files produced by SAW's count command with the files expected by the reader, especially the missing cell.cluster file. Review the alternate SAW analysis output and the proposed Visium-style directory and GEF/GEM inputs. Done requires a decided compatibility scope and a documented, working reading path.

Written by the indexing model from the issue text.

Description

Encountering an issue with missing files when reading BGI's stereo seq data, and there is an inconsistency between the output files from the count command of SAW (a tool under BGI's technology similar to 10x spaceranger) and what is read by spatialdata_io.stereoseq.

Specifically want to know if it is because the SAW output has been updated, making it incompatible with the file reading command of spatialdata_io (there is no cell.cluster file, but it exists in another analysis command of SAW output file).

My proposal is whether there can be a simple reading script (such as one that can just read the 10x Visium output directory and create zarr data) for easy reading(gef gem file).

Dominant language
Python
Stars
103
Forks
64
Avg merge
1h 8m
Merged PRs (30d)
3

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