VEP setup
@HolEv is already working on this.
Since May 14, 2025.
Assessment
This issue has not been assessed yet.
Description
Report
I think, it would be great to have helper functions to support the automatic setup of the VEP cache (we do similar stuff for SnpEff and FAVOR), so bsaically always downloading from https://ftp.ensembl.org/pub/current_variation/indexed_vep_cache/ - The same for the plugins and the reference sequence?
In the local configs reference sequence is GRCh38 - input_fasta: vep_data/genomes/Gencode/Gencode_human/release_40/GRCh38.primary_assembly.genome.fa - while the genome_assembly is said to be GRCh37. Could we have a check, which ensures that this aligns? Are the results for the Docker test Eva did correct?
Version information
No response
- Dominant language
- Python
- Stars
- 25
- Forks
- 8
- Avg merge
- 2m
- Merged PRs (30d)
- 4
Getting set up
- No Dockerfile or Docker Compose file
- No pull request template
- Read the contributing guide
First steps
- Read the whole issue, then the project's contributing guide.
- Comment on the issue to say you are picking it up — it saves two people doing the same work.
- Fork the repository and make your change on a branch.
- Open a pull request that references the issue number.
More from theislab/cellink
-
Difficulty 2/5 1-3 hours Newbie friendliness 62/100
-
ReleaseMay be free again @LArnoldt claimed this 122 days ago, and no pull request is open. Open
-
Implement variant to gene assignment using gencodeMay be free again @HolEv claimed this 211 days ago, and no pull request is open. Openenhancement
-
SnpEff installation instructionsMay be free again @LArnoldt claimed this 432 days ago, and no pull request is open. Openenhancement
-
enhancement
Difficulty 5/5 Over a week Newbie friendliness 15/100
All issues in theislab/cellink
Similar issues
-
[BUG] HTTP lifecycle dispatch treats a NO_PROXY-only environment as corporate egress and skips the resolve-and-pinned sessionPossibly taken @bodapatisaikrishna claimed this today. Open
Difficulty 2/5 1-3 hours Newbie friendliness 76/100
Maintainers usually reply within 1 day
-
external
Difficulty 2/5 1-3 hours Newbie friendliness 65/100
langchain-ai/docs#7652 ·
Maintainers usually reply within 1 day
-
[oblt-aw][autodoc] Document new e2e-secret-leak-artifacts workflow and update e2e-all leaf listOpen
Difficulty 2/5 1-3 hours Newbie friendliness 79/100
elastic/oblt-aw#2513 · 1 comment ·
Maintainers usually reply within 1 day
-
bug p2
Difficulty 2/5 1-3 hours Newbie friendliness 85/100
Maintainers usually reply within 1 day
-
enhancement
Difficulty 1/5 Under an hour Newbie friendliness 75/100
NCAR/CLM-Tutorial#113 · 1 comment ·
Maintainers usually reply within 1 day