ClawBio/ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
Is ClawBio/ClawBio beginner-friendly?
In the last 30 days, ClawBio/ClawBio merged 29 of 78 pull requests from outside contributors, and its maintainers usually reply within 1 day. 7 beginner-friendly issues are open now.
- Stars
- 1.2k
- Forks
- 283
- Open beginner issues
- 7
- Indexed issues
- 34
- Avg merge
- 1d 18h
- Merged PRs (30d)
- 140
- Dominant language
- Python
- License
- No license data
- Last GitHub push
- Oct 14, 2026
- Latest indexed
- Oct 14, 2026
- Contributing guide
- Contributing guide
- Code of conduct
- No code of conduct
- Beginner labels
- help wanted
How to contribute to ClawBio/ClawBio
- Read the contributing guide first: it says how the maintainers want changes proposed, tested and reviewed.
- Pick one of the 7 open beginner-friendly issues below and comment that you want to work on it before you start.
Issues somebody may already be working on are listed last. List everything by date
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Difficulty 2/5 1-3 hours Newbie friendliness 78/100
Maintainers usually reply within 1 day
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Difficulty 2/5 1-3 hours Newbie friendliness 78/100
Maintainers usually reply within 1 day
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Difficulty 2/5 1-3 hours Newbie friendliness 78/100
Maintainers usually reply within 1 day
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Difficulty 2/5 1-3 hours Newbie friendliness 76/100
Maintainers usually reply within 1 day
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Difficulty 2/5 1-3 hours Newbie friendliness 78/100
Maintainers usually reply within 1 day
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question
Difficulty 5/5 Over a week Newbie friendliness 12/100
Maintainers usually reply within 1 day
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question
Difficulty 5/5 Over a week Newbie friendliness 15/100
ClawBio/ClawBio#642 · 3 comments ·
Maintainers usually reply within 1 day
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Difficulty 3/5 Half a day Newbie friendliness 42/100
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 18/100
Maintainers usually reply within 1 day
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Repo cleanupOpen
Difficulty 3/5 1-2 days Newbie friendliness 15/100
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 15/100
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 15/100
Maintainers usually reply within 1 day
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documentation enhancement P2
Difficulty 5/5 Over a week Newbie friendliness 12/100
ClawBio/ClawBio#372 · 1 comment ·
Maintainers usually reply within 1 day
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Difficulty 3/5 1-2 days Newbie friendliness 35/100
ClawBio/ClawBio#360 · 4 comments ·
Maintainers usually reply within 1 day
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Difficulty 3/5 Half a day Newbie friendliness 22/100
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 15/100
ClawBio/ClawBio#313 · 1 comment ·
Maintainers usually reply within 1 day
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Difficulty 3/5 1-2 days Newbie friendliness 50/100
Maintainers usually reply within 1 day
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Difficulty 4/5 3-5 days Newbie friendliness 25/100
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 15/100
ClawBio/ClawBio#107 · 4 comments ·
Maintainers usually reply within 1 day
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Difficulty 5/5 Over a week Newbie friendliness 22/100
ClawBio/ClawBio#106 · 3 comments ·
Maintainers usually reply within 1 day
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Difficulty 4/5 3-5 days Newbie friendliness 30/100
ClawBio/ClawBio#74 · 2 comments ·
Maintainers usually reply within 1 day
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locuscompare-region-render: duplicate eQTL Catalogue rows are paired twice (SORT1 golden: 2,547 pairs, 2,487 unique)Possibly taken @madaraviv claimed this 1 day ago. Open
Difficulty 3/5 1-2 days Newbie friendliness 72/100
ClawBio/ClawBio#692 · 1 comment ·
Maintainers usually reply within 1 day
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ukb-ppp-region-fetch: where does the EUR sample size of 46,673 come from?Possibly taken @madaraviv claimed this 1 day ago. Open
Difficulty 4/5 3-5 days Newbie friendliness 55/100
ClawBio/ClawBio#691 · 1 comment ·
Maintainers usually reply within 1 day
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[Documentation] clinical-trial-finder: example output and README predate the shared reproducibility/ layoutPossibly taken @sooraj-codes claimed this 6 days ago. Openbug
Difficulty 2/5 1-3 hours Newbie friendliness 70/100
ClawBio/ClawBio#630 · 1 comment ·
Maintainers usually reply within 1 day
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pharmgx-reporter: detected DPYD*2A with HapB3 untested should report at least IM, not IndeterminatePossibly taken @manuelcorpas claimed this 10 days ago. Open
Difficulty 3/5 1-2 days Newbie friendliness 22/100
Maintainers usually reply within 1 day
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pharmgx-reporter: methotrexate graded on MTHFR genotype without a CPIC basis; labels overstate activityPossibly taken @abotescu20-maker claimed this 10 days ago. Open
Difficulty 4/5 3-5 days Newbie friendliness 25/100
Maintainers usually reply within 1 day
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wgs-prs: --demo fails at VCF QC on bcftools 1.23 (demo VCF header has no ##contig lines)Possibly taken @ShryukGrandhi claimed this 3 days ago. Openhelp wanted
Difficulty 2/5 1-3 hours Newbie friendliness 85/100
Maintainers usually reply within 1 day
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[Skill] scrna-embedding-audit: score cell embeddings against an in-run PCA baseline (first of a foundation-model series)Possibly taken @krudo-taco claimed this 17 days ago. Open
Difficulty 4/5 3-5 days Newbie friendliness 15/100
ClawBio/ClawBio#541 · 3 comments ·
Maintainers usually reply within 1 day