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Consider use of APE-Gen algorithm

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#709 2 comments 0 reactions 0 assignees View on GitHub

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Assessment

Difficulty
5/5
Estimated time
Over a week
Newbie friendliness
20/100
Issue type
Feature
Clarity
Needs clarification
Activity status
Stale
Tech stack
python

Research direction

Start by reading the linked APE-Gen repository and identifying the current pMHC prediction entry points in pVACtools. Compare how APE-Gen's 3D structure modeling could fit alongside the existing algorithms; the issue does not define an implementation scope or a concrete done condition.

Written by the indexing model from the issue text.

Description

grant prediction_algorithms

From the ITCR meeting. APE-Gen would be quite orthogonal to the current algorithms for pMHC prediction as it is based on 3D structure modeling of the pMHC

https://github.com/KavrakiLab/APE-Gen

Dominant language
Python
Stars
191
Forks
82
Avg merge
3h 34m
Merged PRs (30d)
1

Getting set up

This project ships no dev container, Dockerfile or contributing guide, so setting up is up to you: start from its README, and see our first-contribution guide for the general steps.

First steps

  1. Read the whole issue, then the project's contributing guide.
  2. Comment on the issue to say you are picking it up — it saves two people doing the same work.
  3. Fork the repository and make your change on a branch.
  4. Open a pull request that references the issue number.

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