DifficultyEstimated implementation difficulty for a new contributor, from 1 for very small changes to 5 for expert-level work.
3
Estimated timeA rough time range for an experienced contributor to investigate, implement, test, and prepare a pull request.
1-2 days
Activity statusHow available the issue appears right now: fresh, active, stale, blocked, or waiting on maintainer input.
stale
ClarityHow clearly the issue explains the expected change, acceptance criteria, and next step.
clear
Prerequisites
Stan modeling languagePK/PD conceptsR and knitr
Newbie friendlinessA 1-100 score estimating how approachable this issue is for first-time contributors.
30
Research direction
Review existing example models in the repository to understand the structure. Use the knitr package in R to create a new R Markdown file that defines a basic PK/PD model, simulates data, and fits it using Stan. Consider using the 'rk45' ODE solver in Stan. Ensure the example is well documented and reproducible.