TableModel rejects int8/uint8 instance-key columns although the error message promises 'uint equivalents' (breaks aggregate/to_circles on uint8 labels)

Start in src/spatialdata/models/models.py at TableModel._validate_table_annotation_metadata and run the supplied repro.py with uv run. Check the dtype validation for int8 and uint8, then verify that the reproduction accepts those dtypes and that aggregate(image, by=uint8 labels) succeeds.

[!NOTE]
This whole message is AI-generated. The issue was automatically discovered and reported by an AI agent (Claude) during an autonomous bug hunt on the spatialdata code base. It has not been verified or triaged by a human yet; the needs: triage label is set so that a maintainer can confirm it. The reproduction script below was executed by the agent in an isolated environment (see Environment) and its output is pasted verbatim.

Summary

uint8/int8 instance ids raise TypeError: Only integer (int, np.int16, np.int32, np.int64, and uint equivalents), string ... allowed as dtype for instance_key column in obs. Dtype found to be uint8, while uint16/int64 pass.

Severity (agent's assessment): medium — Labels2DModel.parse(np.zeros(..., dtype=np.uint8)) is common, and aggregate(image, by=uint8_labels) / to_circles(uint8_labels) fail when the result table is built

Where: src/spatialdata/models/models.py::TableModel._validate_table_annotation_metadata (_INT_TYPES = [int, np.int16, np.uint16, np.int32, np.uint32, np.int64, np.uint64])

Expected behaviour

All integer dtypes accepted.

Reproduction

Save as repro.py and run uv run repro.py (the PEP 723 header pins spatialdata to the commit the bug was found on; replace the URL fragment with @main to test the current main branch).

# /// script
# requires-python = ">=3.12"
# dependencies = [
#     "spatialdata @ git+https://github.com/scverse/spatialdata.git@ccf1ea048d054b6624214bf618008a9f9ae223e0",
# ]
# ///
"""TableModel rejects int8/uint8 instance-key columns although the error message promises 'uint equivalents'."""
import warnings
import numpy as np
import pandas as pd
from anndata import AnnData
from spatialdata import aggregate
from spatialdata.models import Image2DModel, Labels2DModel, TableModel

warnings.simplefilter("ignore")
bug = False
for dt in [np.uint8, np.int8, np.uint16, np.int64]:
    obs = pd.DataFrame({"region": pd.Categorical(["lab"] * 3), "instance_id": np.array([1, 2, 3], dtype=dt)})
    try:
        TableModel.parse(AnnData(X=np.zeros((3, 1)), obs=obs), region="lab", region_key="region", instance_key="instance_id")
        print(f"instance_id dtype {dt.__name__:6s}: OK")
    except Exception as e:  # noqa: BLE001
        print(f"instance_id dtype {dt.__name__:6s}: {type(e).__name__}: {str(e)[:70]}...")
        bug = True
# consequence: aggregating an image by uint8 labels fails when the result table is built
labels = Labels2DModel.parse(np.array([[0, 1], [2, 2]], dtype=np.uint8))
image = Image2DModel.parse(np.ones((1, 2, 2)))
try:
    aggregate(values=image, by=labels, agg_func="sum")
    print("aggregate(image, by=uint8 labels): OK")
except Exception as e:  # noqa: BLE001
    print("aggregate(image, by=uint8 labels):", type(e).__name__, str(e)[:70], "...")
print("VERDICT:", "BUG REPRODUCED" if bug else "NOT REPRODUCED")

Observed output

instance_id dtype uint8 : TypeError: Only integer (int, np.int16, np.int32, np.int64, and uint equivalents)...
instance_id dtype int8  : TypeError: Only integer (int, np.int16, np.int32, np.int64, and uint equivalents)...
instance_id dtype uint16: OK
instance_id dtype int64 : OK
aggregate(image, by=uint8 labels): TypeError Only integer (int, np.int16, np.int32, np.int64, and uint equivalents) ...
VERDICT: BUG REPRODUCED

Possible fix direction (unverified)

Replace the whitelist with np.issubdtype(d, np.integer) (plus pandas nullable integer dtypes if desired).

Environment

uv run repro.py with the PEP 723 metadata in the script (fresh, isolated environment; spatialdata built from main @ ccf1ea0 (2026-08-28); Python 3.13, latest releases of the dependencies at run time: pandas 3.0, anndata 0.13, zarr 3.3, dask 2026.8, numpy 2.5, geopandas 1.1, shapely 2.1). macOS (arm64). Also reproduced in a second environment with pandas 2.3.3 / anndata 0.12.11 / numpy 2.4.4 / zarr 3.2.1.

Automatically generated; discovered by an AI agent (Claude) and not yet reviewed by a human.