sipbs-compbiol/BM425-Workshop-2

Selection of a dataset - ideas

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#1 ouverte le 12 mai 2025

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good first issue

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Option 1. PRJNA1168577 from Gannon, Alexa D et al. “Exploring aggregation genes in a P. aeruginosa chronic infection model.” Journal of bacteriology vol. 207,1 (2025): e0042924. doi:10.1128/jb.00429-24

Pros: Some nice data viz in the paper and looks like it ties in nicely with functional analysis (mapping genes identified by RNA-seq to particular pathways); some fluorescence microscopy and other nice figures in the paper; nice explicit links to microbial physiology (different media and mucin added affecting gene expression) Cons: not actually a mutant dataset, so no complementation controls; not sure it would tie in well with the sort of chimera/alpha fold analyses we were mentioning

will add more as I find them...

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